FANCJ Uses Its Motor ATPase to Destabilize Protein-DNA Complexes, Unwind Triplexes, and Inhibit RAD51 Strand Exchange

Mutations in the FANCJ helicase predispose individuals to breast cancer and are genetically linked to the Fanconi anemia (FA) complementation group J. FA is a chromosomal instability disorder characterized by multiple congenital anomalies, progressive bone marrow failure, and high cancer risk. FANCJ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sommers, Joshua A., Rawtani, Nina, Gupta, Rigu, Bugreev, Dmitry V., Mazin, Alexander V., Cantor, Sharon B., Brosh, Robert M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658046/
https://ncbi.nlm.nih.gov/pubmed/19150983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809019200
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak