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Bloom Syndrome Helicase Stimulates RAD51 DNA Strand Exchange Activity through a Novel Mechanism

Loss or inactivation of BLM, a helicase of the RecQ family, causes Bloom syndrome, a genetic disorder with a strong predisposition to cancer. Although the precise function of BLM remains unknown, genetic data has implicated BLM in the process of genetic recombination and DNA repair. Previously, we d...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bugreev, Dmitry V., Mazina, Olga M., Mazin, Alexander V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786030/
https://ncbi.nlm.nih.gov/pubmed/19632996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.029371
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