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Ca(2+) activates human homologous recombination protein Rad51 by modulating its ATPase activity

Human Rad51 (hRad51) protein plays a key role in homologous recombination and DNA repair. hRad51 protein forms a helical filament on single-stranded DNA (ssDNA), which performs the basic steps of homologous recombination: a search for homologous double-stranded DNA (dsDNA) and DNA strand exchange. h...

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Bibliografiske detaljer
Main Authors: Bugreev, Dmitry V., Mazin, Alexander V.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC454202/
https://ncbi.nlm.nih.gov/pubmed/15226506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402105101
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