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New RAD51 Inhibitors to Target Homologous Recombination in Human Cells

Targeting DNA repair proteins with small-molecule inhibitors became a proven anti-cancer strategy. Previously, we identified an inhibitor of a major protein of homologous recombination (HR) RAD51, named B02. B02 inhibited HR in human cells and sensitized them to chemotherapeutic drugs in vitro and i...

詳細記述

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書誌詳細
出版年:Genes (Basel)
主要な著者: Shkundina, Irina S., Gall, Alexander A., Dick, Alexej, Cocklin, Simon, Mazin, Alexander V.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235719/
https://ncbi.nlm.nih.gov/pubmed/34208492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12060920
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