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New RAD51 Inhibitors to Target Homologous Recombination in Human Cells
Targeting DNA repair proteins with small-molecule inhibitors became a proven anti-cancer strategy. Previously, we identified an inhibitor of a major protein of homologous recombination (HR) RAD51, named B02. B02 inhibited HR in human cells and sensitized them to chemotherapeutic drugs in vitro and i...
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| Izdano u: | Genes (Basel) |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8235719/ https://ncbi.nlm.nih.gov/pubmed/34208492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12060920 |
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