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OX40 costimulation turns off Foxp3(+) Tregs
OX40 is a recently identified T-cell costimulatory molecule that belongs to the TNF/TNFR superfamily. OX40 can be expressed by both activated T effector cells and Foxp3(+) Tregs. It is well known that OX40 delivers a potent costimulatory signal to T effector cells, but very little is known about the...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1988917/ https://ncbi.nlm.nih.gov/pubmed/17575071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-070748 |
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