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OX40 costimulation can abrogate Foxp3(+) regulatory T cell-mediated suppression of antitumor immunity
Regulatory T cells (Tregs) play an important role in maintaining immunological tolerance that is one of the main obstacles to overcome for improving antitumor immunity. Recently, the Treg has been shown to constitutively express OX40 (CD134), which is a member of the TNF receptor family that is tran...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018329/ https://ncbi.nlm.nih.gov/pubmed/19455675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24435 |
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