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Fusion Protein of Mutant B7-DC and Fc Enhances the Antitumor Immune Effect of GM-CSF-secreting Whole-cell Vaccine

B7-DC [also known as programmed death ligand 2 (PD-L2)] is a costimulatory molecule expressed predominantly on dendritic cells (DCs) and macrophages. In addition to its coinhibitory receptor, programmed death receptor 1 (PD-1), evidence suggests that B7-DC interacts with an unidentified costimulator...

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Bibliografiske detaljer
Udgivet i:J Immunother
Main Authors: Kojima, Masatsugu, Murata, Satoshi, Mekata, Eiji, Takebayashi, Katsushi, Jaffee, Elizabeth M., Tani, Tohru
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344319/
https://ncbi.nlm.nih.gov/pubmed/24598447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000025
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