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OX40 ligand expressed by DCs costimulates NKT and CD4(+) Th cell antitumor immunity in mice
The exceptional immunostimulatory capacity of DCs makes them potential targets for investigation of cancer immunotherapeutics. We show here in mice that TNF-α–stimulated DC maturation was accompanied by increased expression of OX40 ligand (OX40L), the lack of which resulted in an inability of mature...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2045612/ https://ncbi.nlm.nih.gov/pubmed/17975668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32693 |
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