Comparing the DNA Hypermethylome with Gene Mutations in Human Colorectal Cancer

We have developed a transcriptome-wide approach to identify genes affected by promoter CpG island DNA hypermethylation and transcriptional silencing in colorectal cancer. By screening cell lines and validating tumor-specific hypermethylation in a panel of primary human colorectal cancer samples, we...

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Bibliografische gegevens
Hoofdauteurs: Schuebel, Kornel E, Chen, Wei, Cope, Leslie, Glöckner, Sabine C, Suzuki, Hiromu, Yi, Joo-Mi, Chan, Timothy A, Neste, Leander Van, Criekinge, Wim Van, van den Bosch, Sandra, van Engeland, Manon, Ting, Angela H, Jair, Kamwing, Yu, Wayne, Toyota, Minoru, Imai, Kohzoh, Ahuja, Nita, Herman, James G, Baylin, Stephen B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2007
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988850/
https://ncbi.nlm.nih.gov/pubmed/17892325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030157
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