Convergence of Mutation and Epigenetic Alterations Identifies Common Genes in Cancer That Predict for Poor Prognosis

BACKGROUND: The identification and characterization of tumor suppressor genes has enhanced our understanding of the biology of cancer and enabled the development of new diagnostic and therapeutic modalities. Whereas in past decades, a handful of tumor suppressors have been slowly identified using te...

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Главные авторы: Chan, Timothy A, Glockner, Sabine, Yi, Joo Mi, Chen, Wei, Van Neste, Leander, Cope, Leslie, Herman, James G, Velculescu, Victor, Schuebel, Kornel E, Ahuja, Nita, Baylin, Stephen B
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2008
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429944/
https://ncbi.nlm.nih.gov/pubmed/18507500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0050114
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