Convergence of Mutation and Epigenetic Alterations Identifies Common Genes in Cancer That Predict for Poor Prognosis

BACKGROUND: The identification and characterization of tumor suppressor genes has enhanced our understanding of the biology of cancer and enabled the development of new diagnostic and therapeutic modalities. Whereas in past decades, a handful of tumor suppressors have been slowly identified using te...

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Detalhes bibliográficos
Main Authors: Chan, Timothy A, Glockner, Sabine, Yi, Joo Mi, Chen, Wei, Van Neste, Leander, Cope, Leslie, Herman, James G, Velculescu, Victor, Schuebel, Kornel E, Ahuja, Nita, Baylin, Stephen B
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429944/
https://ncbi.nlm.nih.gov/pubmed/18507500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0050114
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