Convergence of Mutation and Epigenetic Alterations Identifies Common Genes in Cancer That Predict for Poor Prognosis

BACKGROUND: The identification and characterization of tumor suppressor genes has enhanced our understanding of the biology of cancer and enabled the development of new diagnostic and therapeutic modalities. Whereas in past decades, a handful of tumor suppressors have been slowly identified using te...

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Autori principali: Chan, Timothy A, Glockner, Sabine, Yi, Joo Mi, Chen, Wei, Van Neste, Leander, Cope, Leslie, Herman, James G, Velculescu, Victor, Schuebel, Kornel E, Ahuja, Nita, Baylin, Stephen B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429944/
https://ncbi.nlm.nih.gov/pubmed/18507500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0050114
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