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Oxidized, deaminated cytosines are a source of C → T transitions in vivo

The most common base substitution arising from oxidative damage of DNA is a GC → AT transition. In an effort to determine the oxidized lesion(s) that gives rise to this mutation, the mutagenicity of three oxidized cytosines, 5-hydroxycytosine, 5-hydroxyuracil, and uracil glycol, were investigated in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kreutzer, Deborah A., Essigmann, John M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC19878/
https://ncbi.nlm.nih.gov/pubmed/9520408
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