Oxidized, deaminated cytosines are a source of C → T transitions in vivo
The most common base substitution arising from oxidative damage of DNA is a GC → AT transition. In an effort to determine the oxidized lesion(s) that gives rise to this mutation, the mutagenicity of three oxidized cytosines, 5-hydroxycytosine, 5-hydroxyuracil, and uracil glycol, were investigated in...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19878/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3578 |
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