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Defining the optimal parameters for hairpin-based knockdown constructs
Induction of gene silencing using intracellularly expressed silencing triggers has been explored for large-scale loss-of-function screening, creation of knockdown cell lines or knockdown animals, and disease intervention. In all of these applications, the use of highly potent silencing constructs ca...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1986814/ https://ncbi.nlm.nih.gov/pubmed/17698642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.599107 |
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