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Establishment of conditional vectors for hairpin siRNA knockdowns

Small interference RNA (siRNA) is an emerging methodology in reverse genetics. Here we report the development of a new tetracycline-inducible vector-based siRNA system, which uses a tetracycline-responsive derivative of the U6 promoter and the tetracycline repressor for conditional in vivo transcrip...

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Main Authors: Matsukura, Shiro, Jones, Peter A., Takai, Daiya
格式: Artigo
語言:Inglês
出版: Oxford University Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC169962/
https://ncbi.nlm.nih.gov/pubmed/12888529
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