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Defining the optimal parameters for hairpin-based knockdown constructs

Induction of gene silencing using intracellularly expressed silencing triggers has been explored for large-scale loss-of-function screening, creation of knockdown cell lines or knockdown animals, and disease intervention. In all of these applications, the use of highly potent silencing constructs ca...

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Podrobná bibliografie
Hlavní autoři: Li, Leiming, Lin, Xiaoyu, Khvorova, Anastasia, Fesik, Stephen W., Shen, Yu
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986814/
https://ncbi.nlm.nih.gov/pubmed/17698642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.599107
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