Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages

BACKGROUND AND PURPOSE: Macrophages release cytokines that may contribute to pulmonary inflammation in conditions such as chronic obstructive pulmonary disease. Thus, inhibition of macrophage cytokine production may have therapeutic benefit. p38 MAPK may regulate cytokine production, therefore, the...

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Detaylı Bibliyografya
Asıl Yazarlar: Smith, S J, Fenwick, P S, Nicholson, A G, Kirschenbaum, F, Finney-Hayward, T K, Higgins, L S, Giembycz, M A, Barnes, P J, Donnelly, L E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2006
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978438/
https://ncbi.nlm.nih.gov/pubmed/16953188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706885
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