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Activation of p38 Mitogen-Activated Protein Kinase Attenuates Leishmania donovani Infection in Macrophages

Leishmania-induced macrophage dysfunctions have been correlated with altered signaling events. In this work, we report that SB203580, a specific inhibitor of p38 mitogen-activated protein kinases (MAPK), increases Leishmania donovani survival in human peripheral blood mononuclear macrophages. Consis...

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Autori principali: Junghae, Muthoni, Raynes, John G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC128247/
https://ncbi.nlm.nih.gov/pubmed/12183549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.5026-5035.2002
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