Leishmania donovani-Induced Ceramide as the Key Mediator of Akt Dephosphorylation in Murine Macrophages: Role of Protein Kinase Cζ and Phosphatase

Leishmania donovani is an intracellular protozoan parasite that impairs the host macrophage immune response to render it suitable for its survival and establishment. L. donovani-induced immunosuppression and alteration of host cell signaling is mediated by ceramide, a pleiotropic second messenger pl...

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Main Authors: Dey, Ranadhir, Majumder, Nivedita, Bhattacharjee, Surajit, Majumdar, Suchandra Bhattacharyya, Banerjee, Rajdeep, Ganguly, Sandipan, Das, Pradeep, Majumdar, Subrata
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
Assuntos:
Fungal and Parasitic Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865788/
https://ncbi.nlm.nih.gov/pubmed/17220321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01589-06
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