Leishmania donovani Suppresses Activated Protein 1 and NF-κB Activation in Host Macrophages via Ceramide Generation: Involvement of Extracellular Signal-Regulated Kinase

In vitro infection of murine peritoneal macrophages with the protozoan Leishmania donovani has been found to alter the signaling parameters of the host. The present study indicates that the enhancement of intracellular ceramide level in macrophages after infection is a major event relating to macrop...

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Detalhes bibliográficos
Main Authors: Ghosh, Sanjukta, Bhattacharyya, Sandip, Sirkar, Madhumita, Shankar Sa, Gouri, Das, Tanya, Majumdar, Debashis, Roy, Syamal, Majumdar, Subrata
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133095/
https://ncbi.nlm.nih.gov/pubmed/12438359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.6828-6838.2002
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