Leishmania donovani Suppresses Activated Protein 1 and NF-κB Activation in Host Macrophages via Ceramide Generation: Involvement of Extracellular Signal-Regulated Kinase

In vitro infection of murine peritoneal macrophages with the protozoan Leishmania donovani has been found to alter the signaling parameters of the host. The present study indicates that the enhancement of intracellular ceramide level in macrophages after infection is a major event relating to macrop...

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Main Authors: Ghosh, Sanjukta, Bhattacharyya, Sandip, Sirkar, Madhumita, Shankar Sa, Gouri, Das, Tanya, Majumdar, Debashis, Roy, Syamal, Majumdar, Subrata
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133095/
https://ncbi.nlm.nih.gov/pubmed/12438359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.12.6828-6838.2002
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