Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages

BACKGROUND AND PURPOSE: Macrophages release cytokines that may contribute to pulmonary inflammation in conditions such as chronic obstructive pulmonary disease. Thus, inhibition of macrophage cytokine production may have therapeutic benefit. p38 MAPK may regulate cytokine production, therefore, the...

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Detalhes bibliográficos
Main Authors: Smith, S J, Fenwick, P S, Nicholson, A G, Kirschenbaum, F, Finney-Hayward, T K, Higgins, L S, Giembycz, M A, Barnes, P J, Donnelly, L E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978438/
https://ncbi.nlm.nih.gov/pubmed/16953188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706885
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