Lymphocytes genetically modified to express tumor antigens target DCs in vivo and induce antitumor immunity

The exploitation of the physiologic processing and presenting machinery of DCs by in vivo loading of tumor-associated antigens may improve the immunogenic potential and clinical efficacy of DC-based cancer vaccines. Here we show that lymphocytes genetically modified to express self/tumor antigens, a...

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Bibliografiske detaljer
Main Authors: Russo, Vincenzo, Cipponi, Arcadi, Raccosta, Laura, Rainelli, Cristina, Fontana, Raffaella, Maggioni, Daniela, Lunghi, Francesca, Mukenge, Sylvain, Ciceri, Fabio, Bregni, Marco, Bordignon, Claudio, Traversari, Catia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978420/
https://ncbi.nlm.nih.gov/pubmed/17885685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30605
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