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Oxysterols recruit tumor-supporting neutrophils within the tumor microenvironment: The many facets of tumor-derived oxysterols

By binding to the liver X receptor (LXR), oxysterols inhibit the expression of chemokine (C-C motif) receptor 7 (CCR7), hence impairing the migration of dendritic cells to secondary lymphoid organs and inhibiting antitumor immune responses. We have recently identified a new tumor-supporting activity...

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Detalhes bibliográficos
Main Authors: Raccosta, Laura, Fontana, Raffaella, Traversari, Catia, Russo, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897566/
https://ncbi.nlm.nih.gov/pubmed/24490125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26469
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