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Allogeneic lymphocyte-licensed DCs expand T cells with improved antitumor activity and resistance to oxidative stress and immunosuppressive factors

Adoptive T-cell therapy of cancer is a treatment strategy where T cells are isolated, activated, in some cases engineered, and expanded ex vivo before being reinfused to the patient. The most commonly used T-cell expansion methods are either anti-CD3/CD28 antibody beads or the “rapid expansion proto...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Ther Methods Clin Dev
Main Authors: Jin, Chuan, Yu, Di, Hillerdal, Victoria, Wallgren, AnnaCarin, Karlsson-Parra, Alex, Essand, Magnus
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362340/
https://ncbi.nlm.nih.gov/pubmed/26015949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.1
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