Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses

Accumulating evidence support an important role for endogenous bystander dendritic cells (DCs) in the efficiency of autologous patient-derived DC-vaccines, as bystander DCs take up material from vaccine-DCs, migrate to draining lymph node and initiate antitumor T-cell responses. We examined the poss...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Fotaki, Grammatiki, Jin, Chuan, Ramachandran, Mohanraj, Kerzeli, Iliana Kyriaki, Karlsson-Parra, Alex, Yu, Di, Essand, Magnus
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790348/
https://ncbi.nlm.nih.gov/pubmed/29399392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1395126
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