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Single molecule detection of intermediates during botulinum neurotoxin translocation across membranes
The dynamics of Clostridium botulinum neurotoxins (BoNTs) protein-translocation across membranes was investigated by using a single molecule assay with millisecond resolution on excised patches of neuronal cells. Translocation of BoNT/A light chain (LC) by heavy chain (HC) was observed in real time...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1965533/ https://ncbi.nlm.nih.gov/pubmed/17563359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700046104 |
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