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Molecular dissection of botulinum neurotoxin reveals interdomain chaperone function
Clostridium botulinum neurotoxin (BoNT) is a multi-domain protein made up of the approximately 100 kDa heavy chain (HC) and the approximately 50 kDa light chain (LC). The HC can be further subdivided into two halves: the N-terminal translocation domain (TD) and the C-terminal Receptor Binding Domain...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797153/ https://ncbi.nlm.nih.gov/pubmed/23396042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2013.01.007 |
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