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Beltless Translocation Domain of Botulinum Neurotoxin A Embodies a Minimum Ion-conductive Channel
Botulinum neurotoxin, the causative agent of the paralytic disease botulism, is an endopeptidase composed of a catalytic domain (or light chain (LC)) and a heavy chain (HC) encompassing the translocation domain (TD) and receptor-binding domain. Upon receptor-mediated endocytosis, the LC and TD are p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265847/ https://ncbi.nlm.nih.gov/pubmed/22158863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.319400 |
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