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Redox regulation of botulinum neurotoxin toxicity: therapeutic implications
Botulinum neurotoxin causes botulism, and the only effective antidote is the antitoxin. Botulinum neurotoxins are disulfide linked di-chain proteins encompassing a light chain Zn(2+)-protease that is translocated by a heavy chain channel from the synaptic vesicle lumen into the neuronal cytosol wher...
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| Publicado en: | Trends Mol Med |
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| Autor principal: | |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253726/ https://ncbi.nlm.nih.gov/pubmed/25242227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2014.09.005 |
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