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Single molecule detection of intermediates during botulinum neurotoxin translocation across membranes
The dynamics of Clostridium botulinum neurotoxins (BoNTs) protein-translocation across membranes was investigated by using a single molecule assay with millisecond resolution on excised patches of neuronal cells. Translocation of BoNT/A light chain (LC) by heavy chain (HC) was observed in real time...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1965533/ https://ncbi.nlm.nih.gov/pubmed/17563359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700046104 |
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