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Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide

Androgen receptor (AR) is essential for the growth and progression of prostate cancer in both hormone-sensitive and hormone-refractory disease. A DNA-binding polyamide that targets the consensus androgen response element binds the prostate-specific antigen (PSA) promoter androgen response element, i...

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Detalhes bibliográficos
Main Authors: Nickols, Nicholas G., Dervan, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965528/
https://ncbi.nlm.nih.gov/pubmed/17566103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704217104
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