Sequence-specific DNA cleavage mediated by bipyridine polyamide conjugates

The design of molecules that damage a selected DNA sequence provides a formidable opportunity for basic and applied biology. For example, such molecules offer new prospects for controlled manipulation of the genome. The conjugation of DNA-code reading molecules such as polyamides to reagents that in...

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Bibliografiska uppgifter
Huvudupphovsmän: Simon, Philippe, Cannata, Fabio, Perrouault, Loïc, Halby, Ludovic, Concordet, Jean-Paul, Boutorine, Alexandre, Ryabinin, Vladimir, Sinyakov, Alexandre, Giovannangeli, Carine
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2008
Ämnen:
Molecular Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441794/
https://ncbi.nlm.nih.gov/pubmed/18450816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn231
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