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Sequence specific suppression of androgen receptor–DNA binding in vivo by a Py-Im polyamide
The crucial role of androgen receptor (AR) in prostate cancer development is well documented, and its inhibition is a mainstay of prostate cancer treatment. Here, we analyze the perturbations to the AR cistrome caused by a minor groove binding molecule that is designed to target a sequence found in...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486638/ https://ncbi.nlm.nih.gov/pubmed/30838415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz153 |
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