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Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide
Androgen receptor (AR) is essential for the growth and progression of prostate cancer in both hormone-sensitive and hormone-refractory disease. A DNA-binding polyamide that targets the consensus androgen response element binds the prostate-specific antigen (PSA) promoter androgen response element, i...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1965528/ https://ncbi.nlm.nih.gov/pubmed/17566103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704217104 |
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