A carregar...

Antisense Inhibition at the β-Secretase-Site of APP Reduces Cerebral Amyloid and AChE Activity in Tg2576

Misprocessing of β-amyloid precursor protein (APP) leading to the formation of elevated quantities of β-amyloid peptide (Aβ), derived by a cleavage at the β-secretase site (N-671/673aa) and by a cleavage at the γ-secretase site (C-711/713aa) of APP, is considered a key event in the pathogenesis of A...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chauhan, Neelima B., Siegel, George J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1955231/
https://ncbi.nlm.nih.gov/pubmed/17303345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.01.008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!