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Reduction of β-amyloid and γ-secretase by calorie restriction in female Tg2576 mice

Research indicates that female risk of developing Alzheimer’s disease (AD) is greater than that of males. Moderate reduction of calorie intake, known as calorie restriction (CR), reduces pathology in AD mouse models, and is a potentially translatable prevention measure for individuals at-risk for AD...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Schafer, Marissa J., Alldred, Melissa J., Lee, Sang Han, Calhoun, Michael E., Petkova, Eva, Mathews, Paul M., Ginsberg, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346433/
https://ncbi.nlm.nih.gov/pubmed/25556162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.10.043
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