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Phospholipase Cγ2 Contributes to Light-Chain Gene Activation and Receptor Editing
Phospholipase Cγ2 (PLCγ2) is critical for pre-B-cell receptor (pre-BCR) and BCR signaling. Current studies discovered that PLCγ2-deficient mice had reduced immunoglobulin λ (Igλ) light-chain usage throughout B-cell maturation stages, including transitional type 1 (T1), transitional type 2 (T2), and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1952164/ https://ncbi.nlm.nih.gov/pubmed/17591700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02273-06 |
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