Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation

BACKGROUND: Protein aggregation is a hallmark of several neurodegenerative diseases including Huntington's disease and Parkinson's disease. Proteins containing long, homopolymeric stretches of glutamine are especially prone to form aggregates. It has long been known that the small protein...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Howard, Rebecca A, Sharma, Pratima, Hajjar, Connie, Caldwell, Kim A, Caldwell, Guy A, du Breuil, Rusla, Moore, Rhonda, Boyd, Lynn
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952058/
https://ncbi.nlm.nih.gov/pubmed/17663792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-8-32
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