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Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation
BACKGROUND: Protein aggregation is a hallmark of several neurodegenerative diseases including Huntington's disease and Parkinson's disease. Proteins containing long, homopolymeric stretches of glutamine are especially prone to form aggregates. It has long been known that the small protein...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1952058/ https://ncbi.nlm.nih.gov/pubmed/17663792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-8-32 |
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