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Ubiquitination is involved in secondary growth, not initial formation of polyglutamine protein aggregates in C. elegans
BACKGROUND: Protein misfolding and subsequent aggregation are hallmarks of several human diseases. The cell has a variety of mechanisms for coping with misfolded protein stress, including ubiquitin-mediated protein degradation. In fact, the presence of ubiquitin at protein aggregates is a common fea...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368771/ https://ncbi.nlm.nih.gov/pubmed/22494772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-13-10 |
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