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Cell-to-cell Transmission of Polyglutamine Aggregates in C. elegans

Huntington disease (HD) is an inherited neurodegenerative disorder characterized by motor and cognitive dysfunction caused by expansion of polyglutamine (polyQ) repeat in exon 1 of huntingtin (HTT). In patients, the number of glutamine residues in polyQ tracts are over 35, and it is correlated with...

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Detalhes bibliográficos
Publicado no:Exp Neurobiol
Main Authors: Kim, Dong-Kyu, Cho, Kyu-Won, Ahn, Woo Jung, Perez-Acuña, Dayana, Jeong, Hyunsu, Lee, He-Jin, Lee, Seung-Jae
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society for Brain and Neural Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746497/
https://ncbi.nlm.nih.gov/pubmed/29302199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5607/en.2017.26.6.321
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