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Cell-to-cell Transmission of Polyglutamine Aggregates in C. elegans

Huntington disease (HD) is an inherited neurodegenerative disorder characterized by motor and cognitive dysfunction caused by expansion of polyglutamine (polyQ) repeat in exon 1 of huntingtin (HTT). In patients, the number of glutamine residues in polyQ tracts are over 35, and it is correlated with...

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Dades bibliogràfiques
Publicat a:Exp Neurobiol
Autors principals: Kim, Dong-Kyu, Cho, Kyu-Won, Ahn, Woo Jung, Perez-Acuña, Dayana, Jeong, Hyunsu, Lee, He-Jin, Lee, Seung-Jae
Format: Artigo
Idioma:Inglês
Publicat: The Korean Society for Brain and Neural Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746497/
https://ncbi.nlm.nih.gov/pubmed/29302199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5607/en.2017.26.6.321
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