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Enantioselectivity of human AMP, dTMP and UMP-CMP kinases
l-Nucleoside analogues such as lamivudine are active for treating viral infections. Like d-nucleosides, the biological activity of the l-enantiomers requires their stepwise phosphorylation by cellular or viral kinases to give the triphosphate. The enantioselectivity of NMP kinases has not been thoro...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950558/ https://ncbi.nlm.nih.gov/pubmed/17626051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm479 |
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