Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1

Human papillomavirus (HPV) is responsible for cervical cancer, and its role in head and neck carcinoma has been reported. No drug is approved for the treatment of HPV-related diseases but cidofovir (CDV) exhibits selective antiproliferative activity. In this study, we analyzed the effects of CDV-res...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Topalis, Dimitri, Nogueira, Tatiane C., De Schutter, Tim, El Amri, Chahrazade, Krečmerová, Marcela, Naesens, Lieve, Balzarini, Jan, Andrei, Graciela, Snoeck, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891127/
https://ncbi.nlm.nih.gov/pubmed/26824416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7006
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