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Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage
BACKGROUND: Cidofovir (CDV) proved efficacious in treatment of human papillomaviruses (HPVs) hyperplasias. Antiproliferative effects of CDV have been associated with apoptosis induction, S-phase accumulation, and increased levels of tumor suppressor proteins. However, the molecular mechanisms for th...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3681722/ https://ncbi.nlm.nih.gov/pubmed/23702334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-18 |
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