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New prodrugs of Adefovir and Cidofovir
New Adefovir (PMEA) prodrugs with a pro-moiety consisting of decyl or decyloxyethyl chain bearing hydroxyl function(s), hexaethyleneglycol or a (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl unit were prepared starting from the tetrabutylammonium salt of the phosphonate drug and an appropriate alkyl bromi...
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| Publicado no: | Bioorg Med Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Ltd.
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7127853/ https://ncbi.nlm.nih.gov/pubmed/21565516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.04.016 |
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