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Enantioselectivity of human AMP, dTMP and UMP-CMP kinases
l-Nucleoside analogues such as lamivudine are active for treating viral infections. Like d-nucleosides, the biological activity of the l-enantiomers requires their stepwise phosphorylation by cellular or viral kinases to give the triphosphate. The enantioselectivity of NMP kinases has not been thoro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950558/ https://ncbi.nlm.nih.gov/pubmed/17626051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm479 |
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