A host dTMP-bound structure of T4 phage dCMP hydroxymethylase mutant using an X-ray free electron laser

The hydroxymethylation of cytosine bases plays a vital role in the phage DNA protection system inside the host Escherichia coli. This modification is known to be catalyzed by the dCMP hydroxymethylase from bacteriophage T4 (T4dCH); structural information on the complexes with the substrate, dCMP and...

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Publicado no:Sci Rep
Main Authors: Park, Si Hoon, Park, Jaehyun, Lee, Sang Jae, Yang, Woo Seok, Park, Sehan, Kim, Kyungdo, Park, Zee-Yong, Song, Hyun Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6841964/
https://ncbi.nlm.nih.gov/pubmed/31705139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52825-y
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