Synthesis of T4 DNA and bacteriophage in the absence of dCMP hydroxymethylase.

Several lines of research have suggested that the dCMP hydroxymethylase (HMase) coded by bacteriophage T4 is an essential protein in a DNA replication complex, as well as a supplier of hydroxymethyl dCMP for phage DNA synthesis. We show that a mutant [HMase, dCTPase, endonuclease II, endonuclease IV...

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Bibliographic Details
Published in:J Virol
Main Authors: Morton, D, Kutter, E M, Guttman, B S
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1978
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC354265/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/212605/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.28.1.262-269.1978
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