Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide, accounting for an estimated 600,000 deaths annually. Aberrant methylation, consisting of DNA hypomethylation and/or promoter gene CpG hypermethylation, is implicated in the development of a variety of solid tumors, including H...

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Detaylı Bibliyografya
Asıl Yazarlar: Calvisi, Diego F., Ladu, Sara, Gorden, Alexis, Farina, Miriam, Lee, Ju-Seog, Conner, Elizabeth A., Schroeder, Insa, Factor, Valentina M., Thorgeirsson, Snorri S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950459/
https://ncbi.nlm.nih.gov/pubmed/17717605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31457
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